A 58-year-old male presents to the emergency department with acute onset right-sided weakness and aphasia. Symptoms began 2 hours prior to arrival. Non-contrast head CT is negative for hemorrhage. What is the most appropriate next step, assuming no contraindications?
✓ Correct Answer: Option A
For acute ischemic stroke, intravenous alteplase (tPA) is indicated within 4.5 hours of symptom onset, provided there are no contraindications and intracranial hemorrhage has been ruled out by CT.