🏥 USMLE Exam Prep

A 55-year-old woman with type 2 diabetes mellitus is on metformin 1000 mg twice daily. Her last A1c was 8.2%. She has a BMI of 32 kg/m² and a history of stable coronary artery disease. Which medication would be the most appropriate addition to her current regimen?

A Glipizide
B Insulin glargine
C Empagliflozin
D Pioglitazone

✓ Correct Answer: Option C

Given her A1c > 7%, a second agent is needed. Empagliflozin (an SGLT2 inhibitor) is preferred here due to its proven cardiovascular benefits in patients with established cardiovascular disease, in addition to its glucose-lowering and weight-loss effects.

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