🏥 USMLE Exam Prep

A 55-year-old woman with type 2 diabetes mellitus is on metformin 1000 mg twice daily. Her last A1c was 8.2%. She has a BMI of 32 kg/m² and a history of stable coronary artery disease. Which medication would be the most appropriate addition to her current regimen?

A Glipizide
B Insulin glargine
C Empagliflozin
D Pioglitazone

✓ Correct Answer: Option C

Given her A1c > 7%, a second agent is needed. Empagliflozin (an SGLT2 inhibitor) is preferred here due to its proven cardiovascular benefits in patients with established cardiovascular disease, in addition to its glucose-lowering and weight-loss effects.

💡 Why is C) the correct answer?

The correct answer to the question "A 55-year-old woman with type 2 diabetes mellitus is on metformin 1000 mg twice daily. Her last A1c was 8.2%. She has a BMI of 32 kg/m² and a history of stable coronary artery disease. Which medication would be the most appropriate addition to her current regimen?" is Option C: Empagliflozin.

The other options — A) Glipizide, B) Insulin glargine, D) Pioglitazone — are incorrect for this USMLE Exam Prep question. As explained above: Given her A1c > 7%, a second agent is needed. Empagliflozin (an SGLT2 inhibitor) is preferred here due to its proven cardiovascular benefits in patients with established cardiovascular disease, in ad…

📚 About This USMLE Exam Prep Practice Question

This 2-level USMLE Exam Prep question from the Step 2 CK – Clinical Knowledge topic is part of BrainForge Quiz's free exam preparation library. Each question includes the correct answer and a detailed explanation to help you understand the underlying concept, not just memorize the answer.

How to use this page: Read the question above, consider all four options (A through D), then check the highlighted correct answer and explanation. For active timed practice, start a free USMLE Exam Prep practice test or use flashcards for spaced repetition review.

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