A 55-year-old woman with known Addison's disease presents to the emergency department with severe vomiting, abdominal pain, and confusion. Her blood pressure is 75/40 mmHg, heart rate 110 bpm. Laboratory tests reveal hyponatremia and hyperkalemia. What is the most appropriate immediate treatment?

The correct answer to the question "A 55-year-old woman with known Addison's disease presents to the emergency department with severe vomiting, abdominal pain, and confusion. Her blood pressure is 75/40 mmHg, heart rate 110 bpm. Laboratory tests reveal hyponatremia and hyperkalemia. What is the most appropriate immediate treatment?" is Option A: Intravenous normal saline and hydrocortisone.

The other options — B) Oral fludrocortisone and potassium chloride, C) Intravenous dextrose and insulin, D) Oral prednisone and metoclopramide — are incorrect for this USMLE Exam Prep question. As explained above: This patient is presenting with an acute adrenal crisis, characterized by hypotension, gastrointestinal symptoms, and electrolyte abnormalities (hyponatremia, hyperkalemia). Immediate treatment invol…