A 55-year-old woman with a 30-pack-year smoking history presents with progressive dyspnea, non-productive cough, and finger clubbing. High-resolution CT (HRCT) of the chest shows reticular opacities, traction bronchiectasis, and honeycombing predominantly in the subpleural and basal regions. Pulmonary function tests reveal restrictive physiology and reduced diffusing capacity for carbon monoxide (DLCO). Which of the following is the most likely diagnosis?
✓ Correct Answer: Option C
The clinical picture (smoking, clubbing, progressive dyspnea) combined with HRCT findings of subpleural/basal honeycombing, reticular opacities, and traction bronchiectasis, along with restrictive PFTs and reduced DLCO, is highly characteristic of Idiopathic Pulmonary Fibrosis.