🏥 USMLE Exam Prep

A 55-year-old male with a history of type 2 diabetes and hypertension is found to have an incidental adrenal mass on an abdominal CT scan performed for unrelated abdominal pain. The mass measures 3 cm and is homogeneous. His blood pressure is well-controlled, and he denies symptoms of Cushing's syndrome, pheochromocytoma, or hyperaldosteronism. What is the most appropriate next step in the management of this adrenal incidentaloma?

A Referral for adrenalectomy
B Biopsy of the adrenal mass
C Biochemical workup for hormone excess
D Observation with repeat imaging in 6 months

✓ Correct Answer: Option C

Any adrenal incidentaloma requires a biochemical workup to rule out functional tumors, regardless of symptoms. This typically includes evaluation for Cushing's syndrome, pheochromocytoma, and hyperaldosteronism, as many are subclinical.

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