🏥 USMLE Exam Prep

A 48-year-old man with a history of hypertension presents with severe pain, swelling, and erythema in his right great toe, which started suddenly overnight. He recently started a new diuretic medication. What is the most appropriate initial treatment for his acute condition?

A Allopurinol
B Probenecid
C Indomethacin
D Low-dose colchicine daily

✓ Correct Answer: Option C

Indomethacin, an NSAID, is a first-line treatment for acute gout attacks to rapidly reduce pain and inflammation, provided there are no contraindications such as severe renal disease or active peptic ulcer disease.

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