A 45-year-old patient presents with progressive chorea, psychiatric symptoms, and dementia. Family history reveals similar symptoms in the father and grandfather. The disorder is inherited in an autosomal dominant pattern and involves an expansion of CAG trinucleotide repeats. Which genetic disorder is most likely responsible?
✓ Correct Answer: Option C
Huntington's disease is an autosomal dominant neurodegenerative disorder caused by an expansion of CAG trinucleotide repeats in the HTT gene. It classically presents with chorea, psychiatric symptoms, and progressive dementia, often with anticipation.