A 45-year-old male with a history of chronic obstructive pulmonary disease (COPD) presents with worsening dyspnea, increased cough, and change in sputum color from clear to yellow. His oxygen saturation is 90% on room air. Arterial blood gas shows pH 7.30, PaCO2 65 mmHg, PaO2 58 mmHg. Which medication is most appropriate to add to his current regimen (inhaled bronchodilators) at this time?
✓ Correct Answer: Option C
This patient is experiencing an acute exacerbation of COPD with signs of infection and respiratory acidosis. Oral systemic corticosteroids (e.g., prednisone) are indicated to reduce inflammation and improve lung function in moderate-to-severe exacerbations.