A 45-year-old female receiving chemotherapy for breast cancer presents to the emergency department with a temperature of 101.8°F (38.8°C) and chills. Her absolute neutrophil count (ANC) is 300 cells/µL. She has no localizing symptoms of infection. What is the most appropriate initial management?
✓ Correct Answer: Option A
Febrile neutropenia is a medical emergency requiring prompt administration of broad-spectrum intravenous antibiotics after obtaining blood cultures. Delay in antibiotic administration significantly increases mortality risk.