A 42-year-old woman reports experiencing persistent and excessive worry about various aspects of her life, including her job, health, and family finances, for the past 9 months. She also describes muscle tension, difficulty sleeping, restlessness, and impaired concentration. Her symptoms significantly impact her daily functioning. What is the first-line pharmacotherapy for the long-term management of this condition?

The correct answer to the question "A 42-year-old woman reports experiencing persistent and excessive worry about various aspects of her life, including her job, health, and family finances, for the past 9 months. She also describes muscle tension, difficulty sleeping, restlessness, and impaired concentration. Her symptoms significantly impact her daily functioning. What is the first-line pharmacotherapy for the long-term management of this condition?" is Option C: Sertraline.

The other options — A) Alprazolam, B) Buspirone, D) Olanzapine — are incorrect for this USMLE Exam Prep question. As explained above: Selective serotonin reuptake inhibitors (SSRIs), such as sertraline, are considered first-line pharmacotherapy for the long-term management of Generalized Anxiety Disorder due to their efficacy and f…