A 42-year-old man with newly diagnosed HIV infection has a CD4+ T cell count of 75 cells/µL. He is about to start antiretroviral therapy. Which of the following opportunistic infection prophylaxes should be initiated immediately?
✓ Correct Answer: Option D
For HIV patients with a CD4 count less than 200 cells/µL, prophylaxis against Pneumocystis jirovecii pneumonia (PJP) with TMP-SMX is indicated. His CD4 count of 75 cells/µL puts him at high risk for PJP.