🏥 USMLE Exam Prep

A 38-year-old G1P0 woman at 10 weeks gestation presents with persistent nausea and vomiting, resulting in a 5-pound weight loss. She is unable to keep down fluids or food for the past 48 hours. Physical exam reveals dry mucous membranes and orthostatic hypotension. Urinalysis shows ketonuria. What is the most appropriate initial management?

A Prescribe oral ondansetron and discharge home
B Initiate intravenous fluids and antiemetics
C Recommend dietary changes and ginger supplements
D Perform an obstetrical ultrasound to rule out molar pregnancy

✓ Correct Answer: Option B

This patient exhibits signs of hyperemesis gravidarum with dehydration, weight loss, and ketonuria. The initial management involves hospitalization for intravenous fluid rehydration and parenteral antiemetics to prevent further complications. Oral medications and dietary changes are insufficient for severe cases.

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