A 32-year-old woman is diagnosed with major depressive disorder and is started on sertraline. Which of the following pieces of information is most important to counsel her about regarding the medication?

✓ Correct Answer: Option C

Patients should be informed that SSRIs typically take 2-4 weeks (or more) to show significant antidepressant effects, which helps manage expectations and improves adherence. Acute side effects may occur before therapeutic effects are felt.