A 30-year-old woman with Crohn's disease complains of painful, red nodules on her shins. She also reports occasional joint pain, especially in her ankles and knees. Her gastrointestinal symptoms are currently well-controlled with medication. Which extraintestinal manifestation is she most likely experiencing?

The correct answer to the question "A 30-year-old woman with Crohn's disease complains of painful, red nodules on her shins. She also reports occasional joint pain, especially in her ankles and knees. Her gastrointestinal symptoms are currently well-controlled with medication. Which extraintestinal manifestation is she most likely experiencing?" is Option B: Erythema nodosum.

The other options — A) Primary sclerosing cholangitis, C) Pyoderma gangrenosum, D) Ankylosing spondylitis — are incorrect for this USMLE Exam Prep question. As explained above: Erythema nodosum presents as painful, red, subcutaneous nodules typically on the shins and is a common extraintestinal manifestation of inflammatory bowel disease, often associated with arthralgias. …