🏥 USMLE Exam Prep

A 3-month-old infant is brought to the clinic for intermittent cyanosis, especially during feeding or crying spells. On examination, a harsh systolic ejection murmur is heard at the left upper sternal border. Chest X-ray shows a 'boot-shaped' heart. Which congenital heart defect is most likely present?

A Ventricular septal defect
B Atrial septal defect
C Transposition of the great arteries
D Tetralogy of Fallot

✓ Correct Answer: Option D

The classic presentation of Tetralogy of Fallot includes cyanotic spells (tet spells), a harsh systolic murmur from right ventricular outflow tract obstruction, and a 'boot-shaped' heart on CXR due to right ventricular hypertrophy.

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