🏥 USMLE Exam Prep

A 28-year-old woman experiences recurrent, unexpected panic attacks characterized by sudden onset of intense fear, palpitations, sweating, shortness of breath, and a feeling of impending doom. These attacks peak within 10 minutes. She now avoids public places, fearing another attack. These symptoms have been present for 3 months and are not due to substance use or another medical condition. What is the most appropriate initial pharmacotherapy for long-term management?

A Alprazolam as needed
B Sertraline
C Bupropion
D Haloperidol

✓ Correct Answer: Option B

This patient's symptoms are consistent with panic disorder with agoraphobia. Selective serotonin reuptake inhibitors (SSRIs), such as sertraline, are considered first-line pharmacotherapy for the long-term management of panic disorder.

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