A 25-year-old woman with type 1 diabetes presents to the emergency department with severe hyperglycemia (glucose 600 mg/dL), ketonemia, and metabolic acidosis (pH 7.18). She is alert and oriented. Which of the following is the most appropriate initial fluid management?

The correct answer to the question "A 25-year-old woman with type 1 diabetes presents to the emergency department with severe hyperglycemia (glucose 600 mg/dL), ketonemia, and metabolic acidosis (pH 7.18). She is alert and oriented. Which of the following is the most appropriate initial fluid management?" is Option B: 0.9% Normal Saline.

The other options — A) 5% Dextrose in 0.45% Saline, C) 5% Dextrose in Water, D) Lactated Ringer's solution — are incorrect for this USMLE Exam Prep question. As explained above: Initial management of diabetic ketoacidosis (DKA) focuses on rapid rehydration. Isotonic saline (0.9% normal saline) is the preferred initial fluid to restore intravascular volume and improve renal p…