🏥 USMLE Exam Prep

A 16-year-old girl with type 1 diabetes mellitus presents to the emergency department with polyuria, polydipsia, abdominal pain, and confusion. Her blood glucose is 550 mg/dL, arterial pH is 7.15, and bicarbonate is 8 mEq/L. Serum ketones are strongly positive. Which of the following is the most appropriate initial fluid management strategy?

A 5% Dextrose in 0.45% normal saline
B 0.9% Normal saline
C 0.45% Normal saline
D Lactated Ringer's solution

✓ Correct Answer: Option B

Initial fluid resuscitation in diabetic ketoacidosis (DKA) requires isotonic saline (0.9% Normal Saline) to restore intravascular volume and correct dehydration. Dextrose is added later when glucose levels decrease to prevent hypoglycemia.

Related USMLE Exam Prep Questions